• br Bisphosphonate use and breast cancer risk BPs

  2019-06-19

  

  Bisphosphonate use and breast cancer risk BPs are commonly used in the management of postmenopausal osteoporosis. They consist of two phosphate groups, which give them a high affinity to bone. They attach to bone at exposed calcium hydroxyapatite binding sites, which are most accessible at sites

• br This year marks years

  2019-06-18

  

  This year marks 20 years since 189 countries signed the Beijing Declaration and Platform for Action and committed to prioritisation of women\'s empowerment and gender equality. Yet a recently released UN analysis shows that violence against women persists at “alarmingly high levels”. Worldwide, on

• Pregnancies in adolescents year olds and in

  2019-06-18

  

  Pregnancies in adolescents (10–19-year-olds) and in older women (≥35 years) are hazardous for the mother and the child. Despite an almost universal decline in the adolescent during since 1990, adolescent fertility still accounts for 11% of all births worldwide, with 95% of these births occurring in

• Para el Movimiento Social Ind gena

  2019-06-18

  

  Para el Movimiento Social Indígena, el lugar de la protesta es su propio territorio ancestral que es defendido frente pop over here los actores armados. Así, el lugar adquiere por lo menos tres características: a) como sitio donde se realiza la acción colectiva, b) como el motivo y causa de la acci

• br EL CONTEXTO DE LAS NEGOCIACIONES Y LA

  2019-06-18

  

  EL CONTEXTO DE LAS NEGOCIACIONES Y LA AGENDA BILATERAL El avance de Cuba en el fortalecimiento de sus vínculos con América Latina y el Caribe ha sido destacado. En marzo y junio de 2009, Costa Rica y El Salvador, respectivamente, restablecieron relaciones diplomáticas con la Isla, con ello, toda

• DCG IV Supplier We report a case of DCML deficiency and MDS

  2019-06-18

  

  We report a case of DCML deficiency and MDS in a patient with GATA2 mutation who successfully underwent allogeneic stem cell transplantation. Case report At presentation, she had adapted to a hemoglobin level of 79g/l and had only occasional discrete symptoms of her anemia, as fatigue, other con

• GYKI 52466 dihydrochloride When the subject of climate chang

  2019-06-18

  

  When the subject of climate change is raised, people tend to think of extreme heat events, droughts, violent storms, rising sea levels, and floods. Today, we certainly live in an era of severe weather events, which will intensify if human-driven climate change continues unabated. Such events are kno

• br At least people were killed and eight others were

  2019-06-18

  

  At least 69 people were killed and eight others were missing after a landslide in Shenzhen, north of Hong Kong, on Dec 20, 2015. Unlike most landslides triggered by high-intensity rainfall or earthquakes, this orthopoxvirus variola disaster was man-made and triggered by the collapse of a construc

• Analyses such as those used by Burke and

  2019-06-18

  

  Analyses such as those used by Burke and colleagues rely on periodic cross-sectional surveys that are not linked to available or civic registration and vital statistics databases. These surveys are also limited by the inevitable time lag between analyses and feedback to health systems and policy mak

• The acute effects of goserelin on bone have also

  2019-06-18

  

  The acute effects of goserelin on bone have also been evaluated by prospective trials of goserelin+/− adjuvant tamoxifen. The Zoladex in Premenopausal Patients trial randomized 89 women with early breast cancer to goserelin+/− tamoxifen, tamoxifen alone and no endocrine therapy. After 2 years of tre

• Rufinamide Cholangiopathies are a group of rare diseases

  2019-06-18

  

  Cholangiopathies are a group of rare diseases whose primary or secondary target is the cholangiocyte. The onset and subsequent development processes of cholangiopathies are extremely diverse, with causes that are genetic, neoplastic, immune-mediated, idiopathic, infectious, and toxin- or drug-induce

• However this process of government led contracting

  2019-06-18

  

  However, this process of government-led contracting within the context of fragile states raises many important research questions. These questions range from its effect on government legitimacy to health system fragmentation, and long-term sustainability, efficiency, and equitability. Research on so

• br Conclusions Based on our findings

  2019-06-17

  

  Conclusions Based on our findings using a chronic animal model in vivo that repeated VF and defibrillation, not shocks, are associated with striking CaMKII activation, together with accumulating evidence that CaMKII is crucially involved in cellular processes for HF, it is conceivable that CaMKII

• The electrophysiological mechanisms underlying high

  2019-06-17

  

  The electrophysiological mechanisms underlying high frequency activity observed in the PLA during SRAF could be reentry (rotor) or focal discharges (triggered activity). To discriminate between these mechanisms, we perfused ryanodine (10–40μM) or caffeine (5mM) to abolish calcium overload-mediated t

• Introduction Cardiac resynchronization therapy CRT

  2019-06-17

  

  Introduction Cardiac resynchronization therapy (CRT) reduces mortality and morbidity in selected heart failure patients with impaired left ventricular (LV) function and cardiac dyssynchrony [1]. Most patients receive CRT with a defibrillator (CRT-D) because the indications for an implantable cardio

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