• GYKI 52466 dihydrochloride When the subject of climate chang

  2019-06-18

  

  When the subject of climate change is raised, people tend to think of extreme heat events, droughts, violent storms, rising sea levels, and floods. Today, we certainly live in an era of severe weather events, which will intensify if human-driven climate change continues unabated. Such events are kno

• br At least people were killed and eight others were

  2019-06-18

  

  At least 69 people were killed and eight others were missing after a landslide in Shenzhen, north of Hong Kong, on Dec 20, 2015. Unlike most landslides triggered by high-intensity rainfall or earthquakes, this orthopoxvirus variola disaster was man-made and triggered by the collapse of a construc

• Analyses such as those used by Burke and

  2019-06-18

  

  Analyses such as those used by Burke and colleagues rely on periodic cross-sectional surveys that are not linked to available or civic registration and vital statistics databases. These surveys are also limited by the inevitable time lag between analyses and feedback to health systems and policy mak

• The acute effects of goserelin on bone have also

  2019-06-18

  

  The acute effects of goserelin on bone have also been evaluated by prospective trials of goserelin+/− adjuvant tamoxifen. The Zoladex in Premenopausal Patients trial randomized 89 women with early breast cancer to goserelin+/− tamoxifen, tamoxifen alone and no endocrine therapy. After 2 years of tre

• Rufinamide Cholangiopathies are a group of rare diseases

  2019-06-18

  

  Cholangiopathies are a group of rare diseases whose primary or secondary target is the cholangiocyte. The onset and subsequent development processes of cholangiopathies are extremely diverse, with causes that are genetic, neoplastic, immune-mediated, idiopathic, infectious, and toxin- or drug-induce

• However this process of government led contracting

  2019-06-18

  

  However, this process of government-led contracting within the context of fragile states raises many important research questions. These questions range from its effect on government legitimacy to health system fragmentation, and long-term sustainability, efficiency, and equitability. Research on so

• br Conclusions Based on our findings

  2019-06-17

  

  Conclusions Based on our findings using a chronic animal model in vivo that repeated VF and defibrillation, not shocks, are associated with striking CaMKII activation, together with accumulating evidence that CaMKII is crucially involved in cellular processes for HF, it is conceivable that CaMKII

• The electrophysiological mechanisms underlying high

  2019-06-17

  

  The electrophysiological mechanisms underlying high frequency activity observed in the PLA during SRAF could be reentry (rotor) or focal discharges (triggered activity). To discriminate between these mechanisms, we perfused ryanodine (10–40μM) or caffeine (5mM) to abolish calcium overload-mediated t

• Introduction Cardiac resynchronization therapy CRT

  2019-06-17

  

  Introduction Cardiac resynchronization therapy (CRT) reduces mortality and morbidity in selected heart failure patients with impaired left ventricular (LV) function and cardiac dyssynchrony [1]. Most patients receive CRT with a defibrillator (CRT-D) because the indications for an implantable cardio

• En Sumar restar Carlos Fuentes

  2019-06-17

  

  En Sumar, restar, Carlos Fuentes efectivamente colabora con Kátharsis; elige, con cierta ironía, el diálogo escénico, la forma clásica señalada por Aristóteles para la catarsis; pone en acción Auranofin tres personajes, un griego (Pitágoras), a una forma pura (el número uno) y a un mexicano (un vend

• br Discovery of S PR as

  2019-06-17

  

  Discovery of S1PR2 as a CBA sensor in the liver Early studies reported that activation of the ERK1/2 and AKT signaling pathways by CBAs was PTX-sensitive, suggesting a role for a Gαi-linked GPCR. To identify which GPCR activates the ERK1/2 and AKT signaling pathways, the cDNAs encoding more than

• br When many of us contemplate the role

  2019-06-17

  

  When many of us contemplate the role of agriculture in feeding 7·2 billion people, we picture large-scale, industrialised, and efficient systems that produce lots of food that is shipped around the world. Although those systems are relevant, they ER 27319 maleate are only one dimension of what ag

• The launches in London and Boston were just

  2019-06-15

  

  The launches in London and Boston were just that; the beginning of an education and advocacy campaign intended to highlight the pivotal role of surgical care in health system strengthening. The formal Commission report, 32 000 words of synthesis, analysis, recommendations, and indicators, is only on

• The very fact that providing a greater

  2019-06-15

  

  The very fact that providing a greater number of doses of IPTp-SP is incrementally effective, even in settings where the parasite is sensitive, also highlights the potential benefit of interventions using more effective drugs. This finding means there is either scope to improve clearance of existing

• The patient began CODOX M IVAC with rituximab

  2019-06-15

  

  The patient began CODOX-M/IVAC with rituximab [2]. PET and BM after 2 cycles showed complete remission (CR) and this was confirmed 3 and 6 months later after he completed the full treatment course. There was no delay in administration of each cycle (average: 19 days, 16–21). Eight months after thera

14920 records 970/995 page Previous Next First page 上5页 966967968969970 下5页 Last page