• Common and rare SCN A variants may

  2019-05-18

  

  Common and rare SCN10A variants may contribute to AF susceptibility [59,60]. SCN10A mutations (R14L and R1268Q) cause a loss of function of Nav1.5 current, which is expected to reduce excitability and lead to the development of the arrhythmogenic substrate responsible for BrS and AF. A common varian

• A partir de las consideraciones que distinguen la

  2019-05-18

  

  A partir de las consideraciones que distinguen la institucionalización formal e informal, O’Donnell hace un llamado BIBF1120 tener en cuenta las especificidades de las democracias de América Latina y plantea que algunas democracias han subsistido, se han mantenido en el tiempo aun con la presencia d

• De manera puntual ambos gobiernos dejaron sentadas sus posic

  2019-05-18

  

  De manera puntual, ambos gobiernos dejaron sentadas sus posiciones ante el nuevo proceso bilateral para normalizar sus relaciones. En su alocución del 17 de diciembre de 2014, el general Raúl Castro destacó, entre otras cosas, que desde su elección como presidente de los consejos de Estado y de Mini

• Any abnormality causing a loss of

  2019-05-17

  

  Any abnormality causing a loss-of-function in the IKs macromolecular complex may lead to adrenergic-induced imbalance in ventricular repolarization currents and consequent QTc prolongation, which is identified based on the defective response of IKs to PKA stimuli due to mutations in KCNQ1 (-G269S, -

• Induction of labor starting with

  2019-05-17

  

  Induction of labor starting with cervical ripening through the Foley catheter method has been a generally accepted technique and believed to be the safest method to manage pregnant women with an unfavorable tegaserod because it avoids exogenous uterine stimulants and relies on the local and endogen

• Since the first description of epicardial VT ablation with p

  2019-05-17

  

  Since the first description of epicardial VT ablation with percutaneous subxiphoid access in 1996, epicardial mapping and ablation have been widely performed for the treatment of scar-related VT [55]. Svenson et al. reported that protein phosphatase inhibitor epicardial VT circuits are particularly

• silybin br Conclusion Our findings may

  2019-05-17

  

  Conclusion Our findings may help physicians in selecting high-priority patients for bisphosphonate treatment. Zoledronic silybin is indicated for treating patients with MBD from any malignancy [1,35]; however, many patients do not receive treatment (especially in NSCLC and CRPC). Although it may

• A type saddle back type

  2019-05-17

  

  A type 2 (“saddle-back type”) or type 3 ST-segment elevation cannot substitute for a type 1, unless converted to type 1 with fever or sodium drug challenge. A drug challenge–induced type 1 can be used to diagnose BrS only if accompanied by 1 of the criteria specified above. Type 2 is characterized b

• It is noteworthy that in a recent study

  2019-05-16

  

  It is noteworthy that in a recent study, Le Scouarnec et al. [199]. estimated the burden of rare coding variation in arrhythmia susceptibility genes among 167 BrS index patients and compared that with 167 individuals ≥65 years old with no history of cardiac arrhythmia. The authors concluded that, ex

• br Materials and methods br Results br

  2019-05-16

  

  Materials and methods Results Discussion Our results demonstrated that patients who underwent ICD implantation and received 15J-DT exhibited evidence of myocardial damage as indicated by increased serum c-TNT and H-FABP levels. On the other hand, ≤10J-DT (9J or 10J) was associated with an a

• Partamos primero de la v ctima sacrificial Fernando Valle De

  2019-05-16

  

  Partamos primero de la víctima sacrificial: Fernando Valle. Desde su juventud, Fernando es aislado de la sociedad. Su familia lo rechaza, como explica al médico-narrador (120). Una víctima “sacrificable”, según Girard, tiene que ser alguien diferenciado de la sociedad; las víctimas son seres margina

• The great American epidemiologist Bill Silverman taught us t

  2019-05-16

  

  The great American epidemiologist Bill Silverman taught us that the road to hell is paved with good intentions. From 1942, during a 12-year period, more than 10 000 infants were blinded through retinopathy of prematurity because paediatricians recommended a minor increase in the concentration of sup

• Huelga decir que el tono encomi

  2019-05-16

  

  Huelga decir que el tono encomiástico de estos elogios convirtió fexofenadine hydrochloride este género en una tipología discursiva algo maniquea, abrumada por los abusos retóricos y laudatorios. Se trataba tanto de exhibir una trayectoria vital consagrada a la ciencia, como de hacerlo empleando un

• En Am rica Latina los a os noventa

  2019-05-16

  

  En América Latina, los años noventa constituyen la década en la que los reclamos en términos de políticas de identidad en torno tolterodine tartrate la raza y la etnicidad, que habían comenzado en la década anterior, adquirieron su mayor densidad acompañados por las reformas constitucionales que con

• The time to use the distraction osteogenesis apparatus

  2019-05-16

  

  The time to use the distraction–osteogenesis apparatus in children was suggested to be after infection eradication. We used the Ilizarov apparatus immediately following radical debridement to provide stability and prepare for distraction–compression osteogenesis 1 week later. Circular external fixa

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